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496: AI-Powered, Human-Led – Discover the Future of Routing, with OneRail

496: AI-Powered, Human-Led – Discover the Future of Routing, with OneRail

Oct 20, 2025

Bill Catania, Founder and CEO of OneRail, and Adam Isenberg, SVP at the National Association of Wholesale Distributors (NAW), provide complementary perspectives on logistics innovation. Catania explains how OneRail's solution combines a vast logistics network with AI and a human support team to create a unified, optimized fulfillment ecosystem that moves beyond simple routing to provide actionable, real-time insights. Isenberg offers the industry perspective, discussing the challenges distributors face, from workforce changes to rising costs, and how NAW helps members adopt innovative technologies by curating partnerships with solution providers like OneRail. Together, they emphasize that the future of last-mile delivery depends on a human-led, technology-powered approach that leverages data to increase efficiency and empower employees.

496: AI-Powered, Human-Led – Discover the Future of Routing, with OneRail

Today I’m joined by award-winning supply chain brand OneRail.

OneRail is a leading omnichannel fulfillment solution, pairing best-in-class software with logistics as a service, to provide dependability and speed to help businesses meet their delivery promise. With a real-time connected network of 12 million drivers, OneRail matches the right vehicle for the right delivery so brands lower expenses and increase capacity to rapidly scale their businesses.

Today, Bill Catania, founder and CEO at OneRail, and Adam Isenberg, SVP of Strategic Partnerships at the National Association of Wholesale Distributors, join me to talk all about routing. We’ll be talking about traditional routing engines, and why they no longer work. We’ll be shining a light on how exceptions erode profitability in the last mile, and why unification is key. And we’ll be exploring how wholesalers are approaching innovation, the human side of automation, and how OneRail is helping lead us all into the future of last mile.

Guest bio:

Bill Catania, Founder & CEO of OneRail. Bill Catania is the Founder and CEO of OneRail, a leading omnichannel fulfillment solution pairing best-in-class software with logistics as a service that provides dependability and speed to help businesses meet their delivery promise. Bill is a start-up entrepreneur focused on developing and commercializing real-time technology networks. OneRail recently secured series C investment to drive growth and unlock dynamic fulfillment for enterprise retailers and wholesalers. Catania also founded digital coupon pioneer M-Dot Network, the first-of-its-kind retail POS-to-cloud transaction engine, powering the real-time redemption of digital coupons at grocery checkouts throughout North America. At M-Dot, Catania led his team to win the Amazon Web Services Start-Up Challenge, besting more than 1,500 companies from 23 countries. Catania was named to Goldman Sachs Most Exceptional Entrepreneurs of 2024 list at its Builders and Innovators Summit.

 

03:02

An introduction to Adam and the National Association of Wholesale Distributors (NAW).

We’re the leading advocacy and government affairs voice for the distributors, whether you’re moving computer chips, potato chips, or anything in between!
04:34

How listeners can catch up on OneRail content, and why Bill believes in collaboration and connection.

06:03

An overview of OneRail – who they are, what they do, and how they help their customers.

We’re really focused on exercising our horsepower around data science and AI to help internal fleets optimize. When you take that internal optimization, and bolt on third-party, you have something really unique. And over the top of all of that is the human component.
08:12

Traditional routing engines, and their biggest weaknesses.

The problem with routing software in general is that it’s really just a calculator… And there are a lot more constraints now; there’s a tighter SLA window, more demands on the wholesale channel – the routing solution has to contemplate many more variables, and a lot of the solutions out there don’t do that.
10:32

The biggest pain points right now for distributors, and the impact of changing, multi-generational workforces.

The wholesale distribution industry, as vast as it is, are laggers in technology historically. But now, with the advent of so much technology, changing so fast, you’re seeing distributors say: ‘We can’t wait any longer.’
14:33

The business impact of using routing engines that can’t consider all the relevant inputs.

18:13

How exceptions and traditional routing solutions erode profitability, the importance of extracting tribal knowledge in the workplace, and how new technology can allow businesses to make smarter decisions, reducing costs and empowering teams.

It’s about being able to move those levers in real time, and that’s the difference between the visibility era and the actionable insights era, which is where we are today.
24:16

The challenge with change management and how new technology can ease the transition and remove friction.

26:38

The importance of leaning into tech, and how wholesalers are balancing rising delivery expectations and cost pressures with data-driven decision-making.

People want to make informed decisions but they need data, they need intelligence. And when you have a software and a partner that provides you real-time intelligence, that’s how people are going to make those informed decisions to drive their business forward.
30:19

Why many dispatchers ‘swivel-chair’ between systems, and why it’s such a big problem.

33:57

The new mindset, innovative distribution strategies and technologies NAW members are adopting to improve fulfilment and the last mile.

37:04

Why OneRail is uniquely positioned to lead the future of last mile, and why their network is as important as their software.

We have a large network that allows us to execute; not just connect with a courier, but pick a courier because of price, quality, time of day, zip code, SKU… So when we’re matching a delivery, it’s extremely informed.” “It’s a chief supply chain officers best friend, because it allows that professional to let their team do their job, but be more accountable; to leverage external partners and bring their data back in, make sense of it, and apply it.
42:21

How partnerships between wholesalers, carriers and technology providers are shaping the future of last mile.

46:20

The future of last mile, and why the market is finally coming to OneRail.

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